Md Shahidul Islam, in-charge of Joydebpur Railway Station police camp, said the engine and two compartments of Dhaka-bound Panchagarh Express went off the tracks while crossing Mouchak station in Kaliakoir at 9:35pm on Friday.
Shahidul said police were ensuring the comfort and security of the stranded passengers.
Rezaul Islam, in-charge of Joydebpur Railway Junction, said Kurigram-bound Kurigram Express and Dhaka-bound Jamalpur Express trains were stranded at Mirzapur station after the accident.
A rescue team has been called from Dhaka, he said.
The team with a rescue train had already started for the accident site, said Kamalapur Railway Station chief Md Mazharul Haque.